pION INC announces Woodbridge Scientific, LLC, as its National Distributor for the Rainbow Dynamic Dissolution Monitor® System
Woburn, MA�Feb 10, 2010�pION INC today announced the appointment of Woodbridge Scientific, LLC, of Woodbridge, CT, as the exclusive national distributor for the Rainbow Dynamic Dissolution Monitor® System. Led by former pION INC sales manager, Mark Sackler, Woodbridge Scientific, LLC, is also the manufacturer's representative for the entire pION line in much of the northeast U.S.
"We are pleased to have Mark and his company assume this vital role for our fiber-optic line in the USP-related dissolution environment," said Alex Avdeef, CSO/CEO and co-founder of pION."Woodbridge Scientific, LLC is uniquely positioned to apply its considerable experience in the dissolution industry to provide superior sales and customer support."
The Rainbow Dynamic Dissolution Monitor System uses UV fiber-optic technology to rapidly measure the concen- tration of drug substances in conventional dissolution baths without the need for liquid sampling. The solid-state photodiode arrays and fiber optics provide a level of reliability in a maintenance-free system unmatched in the industry.Thesystemwasoriginallydevelopedinthemid- 1990s by scientists at Purdue Pharma, L.P., commercialized in 2001, and later acquired by pION INC.
"I've worked with pION for many years", said Sackler. "We've also been associated with the Rainbow Dynamic Dissolution Monitor System since its prior inception and development by Purdue Pharma, so we're now in a unique position to deliver solid customer sales and support. Along with the support of Vortex Pharma Group of Benson, NC, as channel partner, we are well-positioned to grow and support the Rainbow market."
pION INC will continue to support the instruments of existing Rainbow Dynamic Dissolution Monitor® customers, as well as sell and service its small volume µDISS Profiler™, which also employs the same fiber-optic detector.
About pION INC
pION INC offers ADME-related analytical tools and services to the pharmaceutical and biotechnology laboratories: instruments, supplies, reagents, software, and contract services. Excipient screening is based on the patented solubility/permeability µSOL/PAMPA Evolution™ manual and robotic platforms. Patented in situ fiber-optic UV-based dissolution monitoring systems: the µDISS Profiler PLUS™ for preformulation/delivery research and the Rainbow Dynamic Dissolution Monitor® detection system for time savings in R&D/QC solid dosage forms testing.
About Woodbridge Scientific, LLC
Woodbridge Scientific specializes in tablet dissolution quality control instrumentation, dissolution baths, and magnetic bead separations. Woodbridge represents pION INC, Logan Instruments, Vortex Pharma Group, and Soma Engineering.
Date: 10 February 2010
Contact:
Dr. Cynthia Berger
Chief Financial Officer
pION INC, 5 Constitutional Way, Woburn, MA 01801
tel +1 781 935 8939
fax+1 781 935 8938
pion@pion-inc.com
www.pion-inc.com
Mark Sackler
General Manager
Woodbridge Scientific, LLC
tel +1 203-387-5750
info@woodbridgescientific.com
| SOTAX AG | Tel. +41 61 487 54 54 | info@sotax.com |
| Binningerstrasse 106 | Fax +41 61 482 13 31 | www.sotax.com |
| CH-4123 Allschwil 1 |
PALL CORPORATION TEAMS UP WTH SOTAX ON SYRINGE FILTERS
Pall Corporation and SOTAX Deliver Cost-Effective Automation Certified Solutions for Automated Pharmaceutical Testing Systems
Port Washington, NY�March 18, 2010�Pall Corporation (NYSE: PLL), a global leader in filtration, separation, and purification, has announced a long-term joint marketing agreement with the SOTAX Group that will include Pall Acrodisc® PSF syringe filters in all SOTAX dissolution systems for solid dosage forms. The exclusive agreement is the initial step that allows the companies to begin delivering complete, certified solutions that save time and testing costs for pharmaceutical laboratories.
Pall Acrodisc® PSF syringe filters are used by research and analytical laboratories to help expedite automated sample processing. First introduced in 1973, Pall's Acrodisc® syringe filters provide improved retention efficiency to help extend HPLC column life by as much as 46-fold.The multi-layered prefilter provides two to four times the throughput of standard glass fiber prefilter devices to allow for quick and easy filtration of samples that are difficult to filter.The PSF housing has been designed for smooth operation in automated systems and operating pressures, eliminating filter burst.
SOTAX is a provider of high-quality dissolution testing systems, assay and content uniformity workstations along with physical tablet testing instruments for the pharmaceutical industry. SOTAX automated systems include the SOTAX AT70BS60 and Zymark Multidose for fully automated dissolution systems, the SOTAX AT 7smart with FS 7 Automated Filter Station for automating single dissolution tests, the SOTAX CTS and Zymark TPW3 automated sample preparation systems for content uniformity and assay testing, and the Zymark APW Active Pharmaceutical Ingredient Processing workstation.
"By exclusively recommending Pall Acrodisc® PSF technology as part of our testing systems, we can ensure we are providing the pharmaceutical industry with a significantly improved automated dissolution process for multiple unattended tests. This includes applications for media preparation and delivery, automated dosage introduction, automated sampling, filtering, and sample analysis," said Gilles Devidts, Head of Product Management, SOTAX.
At the start of this agreement, all new SOTAX AT 70smart Dissolution systems and SOTAX CTS Content Uniformity test systems will include the Pall Acrodisc® PSF syringe filters. Filter refills will be available directly from Pall Life Sciences through its regular sales and distribution channel.
"This marketing partnership with SOTAX advances the performance of the automated laboratory analysis platform," said Larry O'Connell, Senior Vice President, Global Lab Products for Pall Life Sciences."Customers can now obtain the dual benefits associated with SOTAX and Pall technology to achieve superior analysis and performance."
To learn more about Acrodisc® PSF syringe filters, visit www.pall.com/lab
To order, call 1-800-521-1520 in the U.S./Canada or LabCustomerSupport@pall.com
For more information on how SOTAX can automated your dissolution or content-uniformity testing, visit our website www.sotax.com or contact your local SOTAX office.
Phares SIF Powder: New '5 for 4' Promotion
If you prepare FeSSIF or FaSSIF, you might be interested in Phares SIF Powder. This innovative product enables you to make highly reproducible FeSSIF or FaSSIF in an instant. A new '5 for 4' special promotion on this line has just been launched on www.ePhares.com For every 4 units of SIF Powder purchased, you now get 1 free, an offer valid across all 3 bottle sizes. ePhares.com has recently been upgraded to include fresh video content and more in-depth technical information. The website now accepts payment by American Express, and customers can also benefit from reduced shipping costs.
| SOTAX AG | Tel. +41 61 487 54 54 | info@sotax.com |
| Binningerstrasse 106 | Fax +41 61 482 13 31 | www.sotax.com |
| CH-4123 Allschwil 1 |
MALLINCKRODT BAKER PARTNERS WITH SOTAX FOR DILUT-IT™ DISSOLUTION MEDIA CONCENTRATES
Mallinckrodt Baker's J.T.Baker® DILUT-ITTM Dissolution Media Concentrates Combined with SOTAX® Dissolution Testing Equipment Offer a One-Stop Solution to Help Streamline Dissolution Testing
Phillipsburg, New Jersey�March 1, 2010�Covidien (NYSE: COV), a leading global provider of healthcare products, today announced a global alliance between its Mallinckrodt Baker performance chemicals business and the SOTAX Group to promote J.T.Baker® DILUT-IT™ dissolution media concentrates with SOTAX® as a one-stop solution to help increase lab productivity.
Mallinckrodt Baker is a worldwide leader in manufactur- ing high-purity chemicals, while SOTAX is a worldwide leader in developing pharmaceutical testing systems.
Under the alliance, SOTAX will recommend Mallinckrodt Baker's J.T.Baker® DILUT-IT™ dissolution media concen- trates for use with its dissolution testing equipment and dissolution media preparation stations. Customers with SOTAX® systems will also be able to request J.T.Baker® DILUT-IT™ dissolution media concentrates directly from SOTAX under a specialty distribution agreement. By eliminating weighing and mixing variables, J.T.Baker® DILUT-IT™ dissolution media concentrates greatly increase reproducibility and help reduce operator error, rework, and waste. Manufactured in a controlled, ISO-certified environment in accordance with USP guidelines, J.T.Baker® DILUT-IT™ dissolution media concentrates are packaged to stringent fill tolerances to ensure lot-to-lot consistency. Cost savings are as much as a third of the cost compared to pre-made dissolution media from Chata.
"We chose to work with Mallinckrodt Baker not only because of their quality products, but also because they share our commitment to improving laboratory processes and productivity," said Gilles Devidts, Head of Product Management, SOTAX Group."By using the J.T.Baker® DILUT-IT™ dissolution media concentrates in conjunction with the SOTAX® AT 70smart automated system, the Zymark® MultiDose G3 workstation, or the MPS Media Preparation System for manual and semi-automated dissolution baths, we are now able to provide our customers with a complete dissolution testing solution."
For more information about J.T.Baker® DILUT-IT™ dissolution concentrates, visit http://www.mallbaker.com/ overview/lab/DILUT-IT_dissolution.asp
For pricing and ordering information, please visit www.sotax.com or contact your local SOTAX office.
Next Generation Dissolution Apparatus from Varian, Inc. Blends Flexibility with Automation
708-DS Integrates with Varian's Latest UV and HPLC Analytical Solutions
Palo Alto, CA�Varian, Inc. (NasdaqGS: VARI) announced today the availability of its next-generation dissolution apparatus designed for testing tablets, capsules, and other dosage forms. The 708-DS supports a broad set of applications ranging from manual dissolution testing to automated, high-throughput analysis. It provides extensive flexibility to match the needs of individual laboratories, whether in research or testing. Integration with either the new Varian UV or LC Dissolution Systems will save time and reduce the potential for sample handling errors.
For dissolution testing laboratories, robust instrumentation and ease of use are paramount. Each laboratory has its own clearly defined set of Standard Operating Procedures (SOPs) that dictate how analyses are performed. At the same time, customers appreciate the flexibility to make choices about the automation of certain tasks. The 708-DS with traditional water bath and TruAlign™ vessels supports several innovative automation options, including automated media temperature sensing, dosage delivery, and sampling. Customers can decide for themselves which automation options make sense for their laboratories.
For increased productivity beyond manual and semi-automated testing, the 708-DS offers integration capabilities for UV and HPLC analytical finishes. Varian's UV Dissolution System provides superior online UV analysis with a choice of either multicell or fiber-optic configurations. The Varian LC Dissolution System is a fully integrated, automated, online HPLC dissolution system that can provide the maximum amount of information about each sample. Both the UV and LC Dissolution Systems significantly reduce the time required for complete sample analysis. Varian's breadth of products offer the ability to obtain complete dissolution, UV, and HPLC solutions from one provider, eliminating concerns over integrating components from multiple vendors.
"The introduction of the 708-DS is clear evidence that Varian continues to listen to our customers and make a significant investment in providing answers for their needs," said Martin O'Donoghue, Senior Vice President, Scientific Instruments."Our position as a leading manufacturer of pharmaceutical testing equipment is further enhanced by the ability to deliver complete dissolution, UV, and HPLC solutions from one provider."
Varian's leadership in dissolution extends far beyond offering innovative dissolution products. We provide customers with a complete solution including qualification services, training, SOP guidance and support, and technical support for equipment. For the broader dissolution community, Varian provides educational seminars, a Dissolution Hotline, method development support, regulatory updates and guidance, and the helpful vendor-neutral Dissolution Discussion Group (DDG) online forum.
For more technical information about Varian dissolution products, please visit http://www.varianinc.com/dissolution/
About Varian, Inc.: Varian, Inc. is a leading worldwide supplier of scientific instruments and vacuum technologies for life science, environmental, energy, and applied research and other applications. The company provides complete solutions, including instruments, vacuum products, laboratory consumable supplies, software, training, and support through its global distribution and support systems. Varian, Inc.'s common stock is traded on the NASDAQ Global Select Market under the symbol "VARI." Further information is available on the company's Web site at www.varianinc.com
For more information, contact:
Public Relations
Varian, Inc.
+1 925-942-4703
pr@varianinc.com
NEWS RELEASE
Copley Scientific Launches World's First Commercial Apparatus for Dissolution Testing of Inhaled Drugs
Nottingham, UK�January 25, 2010�Copley Scientific has launched the world�s first commercially available apparatus designed specifically for dissolution testing of inhaled drug formulations. Based on a concept developed by Professor Jason McConville and his team at the College of Pharmacy, University of Texas, a new NGI dissolution cup and membrane holder enables dissolution testing of size-fractionated particles selected from the emitted dose. Simple to use and employing analytical methodology based on established pharmacopeial techniques for transdermal patches, it provides information that allows developers to more closely tailor inhaled drug delivery. The launch underlines Copley Scientific�s commitment to commercializing new analytical techniques for inhaled product testing and providing the very best tools for development and QC.
Dissolution testing is widely applied in the develop- ment and manufacture of oral dosage forms but is not yet in widespread use for inhaled products where the prime focus is successful deposition in the lung. Currently there are no official dissolution test methods for inhaled products. However, increasing use of the pulmonary route to deliver larger molecules and/or systemic therapies means growing emphasis on the rate of active pharmaceutical ingredient dissolution. Dissolution information allows the development of more sophisticated inhalation products with delayed release characteristics or more closely controlled drug delivery profiles.
In dissolution testing for inhaled drugs, the respirable portion of the emitted dose is of primary interest. The new solution from Copley Scientific addresses this by integrating conventional tablet dissolution testing equipment within the Next Generation Impactor (NGI), a system used routinely for aerodynamic particle size measurement to size-fractionate a sample. The NGI dissolution cup fits into a conventional NGI cup tray but has a 50-mm removable insert in the impaction area, allowing the collection of particles lying in a specific size fraction. The collected sample is tested in a dissolution tester using a procedure very similar to the �Paddle over Disc� technique described in the pharmacopoeia for transdermal patches. Copley Scientific also offers a similar solution for use with the Andersen Cascade Impactor. www.copleyscientific.com
About Copley Scientific
Copley Scientific is recognized as the world�s leading manufacturer of inhaler test equipment and is a major supplier of test equipment for pharmaceutical solid dosage forms, including tablet dissolution, disintegration, friability, hardness, and powder testers. The company has offices in the UK and Switzerland and a partnership with aerosol particle science experts MSP Corporation in North America. Copley�s broad range of testing products for metered-dose inhalers, dry-powder inhalers, nebulizers, and nasal sprays are supplied and supported worldwide through close relationships with specialist distributors. Serving the pharmaceutical and associated industries, Copley offers an extensive range of equipment for research, development, and quality control, as well as full validation and aftersales service, providing a single source for products that meet individual needs. www.copleyscientific.com
For further information
Press information
Trish Appleton, Kapler Communications Knowledge
Centre, Wyboston Lakes, Great North Road, Wyboston,
Bedfordshire, MK44 3BY, UK
Tel: +44 (0)1480 479280; Fax: +44 (0)1480 470343
trish@kapleronline.com
Company contact:
Mark Copley, Sales Director, Copley Scientific Limited
Colwick Quays Business Park, Private Road No. 2, Colwick,
Nottingham UK NG4 2JY
Tel: +44 (0)115 961 6229 Fax: +44 (0)115 961 7637
m.copley@copleyscientific.co.uk
www.copleyscientific.com
North American Distribution
MSP Corporation 5910 Rice Creek Parkway, Suite 300,
Shoreview, MN 55126 USA
Tel: +1 651-287-8100 Fax: +1 651-287-8140
Email: sales@mspcorp.com
www.mspcorp.com