August 2011 Volume 18 Issue 3

Intrinsic Dissolution as a Tool for Evaluating Drug Solubility in Accordance with the Biopharmaceutics Classification System Michele G. Issa and Humberto G. Ferraz Pharmacy Department, Pharmaceutical Sciences School, University of São Paulo, São Paulo, Brazil Corrigendum to "Feasibility Study on Qualification of USP Dissolution Apparatus 1 and 2 Using the Enhanced Mechanical Calibration Procedure" Brian Yan, Xujin Lu, and Ruben Lozano Analytical & Bioanalytical Development, Bristol-Myers Squibb Company, New Brunswick, NJ 08903-0191 Simulated Biological Fluids with Possible Application in Dissolution Testing Margareth R. C. Marques1, Raimar Loebenberg2, and May Almukainzi2 1U.S. Pharmacopeia, 12601 Twinbrook Parkway, Rockville, MD USA 2Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada Drug Transport Mechanisms from Carbopol/Eudragit Verapamil Sustained-Release Tablets Sandile M. Khamanga and Roderick B. Walker Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa Formulation and Optimization of Nanosuspensions for Enhancing Simvastatin Dissolution Using Central Composite Design Vikram M. Pandya1, Jayvadan K. Patel2, and Dhaval J. Patel3 1B.S.Patel Pharmacy College, Linch, Mehsana, Gujarat, India 2Nootan Pharmacy College, Gujarat, India 3Shree Krishna Institute of Pharmacy, Shankhalpur, Mehsana, Gujarat, India Dissolution Method for Milnacipran Hydrochloride Capsules: Development, Validation, and Study of Changes in Dissolution Rate after Storage Carolina Lupi Dias, Rochele Cassanta Rossi, Lisiane Bajerski, and Pedro Eduardo Fröehlich Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS). Av. Ipiranga, Porto Alegre, Brasil Studies in Dissolution Enhancement of Ezetimibe by Solid Dispersions in Combination with a Surface Adsorbent Komal R. Parmar, Sunny R. Shah, and Navin R. Sheth Department of Pharmaceutical Sciences, Saurashtra University, Gujarat, India Dissolution Behavior and Thermodynamic Stability of Fused-Sugar Dispersions of a Poorly Water-Soluble Drug Ghanshyam Singh, Gulshan Chhabra, and Kamla Pathak Department of Pharmaceutics, Rajiv Academy for Pharmacy, Chattikara, Mathura Uttar Pradesh, India Gastroretentive Orlistat Microspheres: Formulation, Characterization, and In Vitro Evaluation S. B. Sateesha1, B. Prakash Rao1, A. J. Rajamma2, and L. V. G. Nargund3 1Department of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bangalore, India 2Department of Pharmacognosy, KLE University College of Pharmacy, Bangalore, India 3Department of Pharmachemistry, Nargund College of Pharmacy, Bangalore, India Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD