2007 Issues

February 2007 Volume 14 Issue 1

Vibration Measurements on Dissolution Systems and Effects on Dissolution of Prednisone Tablets RS Saroj Vangani,Tawnya Flick,Germinia Tamayo, Rick Chiu, and Nina Cauchon Small Molecule Pharmaceutics, Amgen Inc,Thousand Oaks, CA In VitroñIn Vivo Correlation: Importance of Dissolution in IVIVC J-M. Cardot, E. Beyssac, and M.Alric Biopharmaceutical Department, UFR Pharmacie Clermont-Ferrand, France Perturbation Study of Dissolution Apparatus VariablesóA Design of Experiment Approach Joseph Eaton,Gang Deng,Walter W. Hauck, William Brown, Ronald G. Manning, and Samir Wahab US Pharmacopeia, Rockville, MD Evaluation of Glass Dissolution Vessel Dimensions and Irregularities Mark R. Liddell,Gang Deng,Walter W. Hauck, William E. Brown, Samir Z.Wahab, and Ronald G. Manning US Pharmacopeia, Rockville,MD Dissolution Highlights of the AAPS Annual Meeting Vivian Gray1 and Saji Thomas2 1Dissolution Technologies,Hockessin, DE 2Par Pharmaceuticals,Woodcliff Lake,NJ Book Review: Injectable Dispersed Systems, Formulation, Processing and Performance Edited By Diane J. Burgess, Published by Taylor and Francis Group, Boca Raton FL, 2005 ISBN 0-8493-3699-6 Anne-FranÁoise Aubry, Ph.D. Bristol-Myers Squibb, 1 Squibb Drive, New Brunswick, NJ 08903 Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD

May 2007 Volume 14 Issue 2

Commentaries on Mechanical versus Chemical Calibration Contributing authors: Royal Hanson, Hanson Research; Saroj Vangani,Amgen; Alger Salt, GSK; John Burmicz, Pharma Test; Saji Thomas, Par Pharmaceutical, Jeff Seely,Distek; Johannes Kraemer, PHAST Laboratories, Jon Kretz,Watson Pharmaceuticals; and Bryan Crist,Varian The Effects of Buffer Molarity,Agitation Rate, and Mesh Size on Verapamil Release from Modified- Release Mini-Tablets Using USP Apparatus 3 Sandile M. M. Khamanga and Roderick B.Walker Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa Application of USP Apparatus 7 to In Vitro Drug Release in Scopolamine Transdermal Systems Marilyn X. Zhou,Duane Shoudt,Genaro Calderon, and Min Feng Analytical Research and Development, Aveva Drug Delivery Systems,Miramar, FL Attempt to Design Continuous DissolutionñAbsorption System Using Everted Intestine Segment for In Vitro Absorption Studies of Slow Drug Release Formulations Vinita V. Kale, Rahul H. Kasliwal, and Jasmin G.Avari Department of Pharmaceutical Sciences, Rashtrasant Tukdoji Maharaj Nagpur University Campus, Maharashtra. India Technical Note: Total Dissolved Gas Pressure (TDGP) Sensing in the Laboratory Brian G.DíAoust Common Sensing Inc., Clark Fork, ID Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD

August 2007 Volume 14 Issue 3

Proposed Change to Acceptance Criteria for Dissolution Performance Verification Testing Walter W. Hauck, Ronald G. Manning, Todd L. Cecil, William Brown, Roger L. Williams US Pharmacopeia, 12601 Twinbrook Parkway, Rockville, MD Challenges with Dissolution Testing and Quality Assessment for Commercial Feverfew Products Ping Jin1, Shadi Madieh2, and Larry L. Augsburger3 1United States Pharmacopeia, 12601 Twinbrook Parkway, Rockville, Maryland 20852, USA 2Glaxo Smith Kline, 709 Swedeland Road, King of Prussia, PA 19406, USA 3University of Maryland, Baltimore, School of Pharmacy, 20 N. Pine Street, Baltimore, MD 21201, USA A Comparison of the Technical Quality of American and Japanese Ranitidine Tablets Makoto Otsuka1, Yuka Akizuki2, Kuniko Otsuka3, Shinichiro Yanagisawa4, Isao Kamae4, and James A. Jorgenson5 1Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University, Shinmachi 1-1-20, Nishi-Tokyo, Tokyo 202-8585, Japan 2Kobe Pharmaceutical University, Motoyama-Kitamchi 4-19-1, Higashi-Nada, Kobe 658-8558, Japan 3School of Medicine, Showa University, Hatanodai 1-5-8, Shinagawa, Tokyo 142-8555, Japan 4Faculty of Medicine, Kobe University, Kusunokichou 7-5-1, Chuo, Kobe 650-0017, Japan 5University Hospital Pharmacy, University of Utah, 50 North Medical Drive, Salt Lake City, Utah 84132, USA Activities of the AAPS In Vitro Release and Dissolution Testing Focus Group Kailas Thakker1 and Vivian Gray2 1Analytical Solutions, Durham, NC 2V.A. Gray Consulting, Hockessin, DE Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD

November 2007 Volume 14 Issue 4

Simplified Biorelevant Media for Screening Dissolution Performance of Poorly Soluble Drugs Thomas Zoeller and Sandra Klein Institute of Pharmaceutical Technology, Johann Wolfgang Goethe University, Frankfurt am Main 60438, Germany The Comparison of In Vitro Release Methods for the Evaluation of Oxytocin Release from PluronicÆ F127 Parenteral Formulations F.A. Chaibva and R.B. Walker Department of Pharmaceutics, Rhodes University, Grahamstown, South Africa, 6140 Differences in In Vitro Dissolution Rates Using Single-Point and Multi-Point Sampling Limin Zhang1, Khanh Ha1, Brent Kleintop1, Shannon Phillips2, Barry Scheer1 1Analytical Research & Development, Bristol-Myers Squibb Pharmaceutical Research Institute, New Brunswick, NJ 2The Dow Chemical Company, Texas Operations, Freeport, TX A Comparative In Vitro Assay of Drug Release Performance of Pyridostigmine Bromide Tablets Noelia L. Gonzalez Vidal1,2, Patricia D. Zubata1, Laura D. Simionato1, Irma Ercolano1, and Maria T. Pizzorno1,2 1Cátedra Control de Calidad de Medicamentos, Facultad de Farmacia y Bioqu�mica, Universidad de Buenos Aires, Jun�n 956, 1113 Buenos Aires, Argentina 2Cátedra Control de Calidad de Medicamentos, Departamento de Biolog�a, Bioqu�mica y Farmacia, Universidad Nacional del Sur, San Juan 670, 8000 Bah�a Blanca, Argentina Technical Note: Miniaturized Intrinsic Dissolution Rate (Mini-IDR™) Measurement of Griseofulvin and Carbamazepine Cynthia M. Berge1, Oksana Tsinman1, Dmytro Voloboy1, Dana Lipp1, Steven Stones2, and Alex Avdeef1 1pION INC, 5 Constitution Way, Woburn, MA 01801, USA 2Heath Scientific Co Ltd., Bletchley, MK1 1SW, UK Meeting Report: AAPS/FDA Workshop on BE, BCS, and Beyond Vivian Gray V. A. Gray Consulting, Hockessin, DE Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD