SYSTEM 4000 and Logan Instruments Corp.

After months of research, LOGAN is proud to present the SYSTEM 4000, an automated USP apparatus 4 sampling system.

The SYSTEM 4000 contains five essential devices. DISSO 4000 is the USP apparatus 4, for closed-loop systems, and it is automated by a system controller and sample collector. The MC-4000 Media Changer and MST-4000 Media Station can be added for open-loop systems. The system controller controls the SYSTEM 4000’s temperature and sampling interval; the accuracy of the flow rate is controlled by syringe pumps; the sample collector controls the media flow either for sampling or flow-thru. The MST-4000 Media Station contains four large media bottles with selected pH media solution, and all four are pre-heated and ready for transfer into MC-4000 Media Changer. The MC-4000 Media Changer is a necessity because it contains a media mixing station, which is a unique buffer system that allows four types of pH media to mix and transfer steadily.

What makes the LOGAN SYSTEM 4000 stand out among other similar products is the fact that it contains several unique designs. In the DISSO 4000, there is a power lift system to lift the flow cell assembly module. Inside the flow cell assembly, there is a tower of filters to avoid any clogging for more productive filtering. The constant flow rate accuracy is generated by dual syringe pumps; a pulsation device can be added in the system that allows variable pulses to be created in the flow thru loop, which converts the constant flow to pulsating rhythms. Flow cell assembly is inside a water jacket system for better temperature control. The flow-thru cell assembly module (DISSO 412) can be mounted on existing Logan dissolution baths, making it easy to convert from USP apparatus 1 and 2 to USP 4. This module can be purchased separately, and it supports closed-loop experiments, or add MC-4000 and MST-4000 for open-loop experiments. And as mentioned above, the unique buffer chamber and setting experiments to closed loop or optional open loop modes are also LOGAN’s exclusive designs. LOGAN sincerely hopes that this CFR 21-compliant system can meet the needs to anyone who uses it.

LOGAN is a place of creativity and diversity. The inclusivity makes new employees feel like home, where questions are encouraged to be asked freely and open communication is expected. We believe that success requires teamwork. Do not hesitate to contact us if you want to join LOGAN and be a part of our journey. We also hope that when the coronavirus situation gets under control, we could see you at the next AAPS Pharma Sci 360. Stay tuned for more excellent news.