1998 Issues


Volume 5, Issue 1, February 1998

Techniques for Measuring InVitro Release from Semisolids

Joel L. Zatz, Ph.D. and Judith D. Segers, M.S.
Rutgers College of Pharmacy, Piscataway, NJ

International Workshop: The Role of theBiopharmaceutical Classification System and IVIVC on the Approval of Oral Drug Products

Pooled Dissolution Testing: A Primer

Royal Hanson (1), Michael E. Swartz, Ph.D. (2), and Robert J. Jarnutowski (3)
(1) Hanson Research Corp., Chatsworth, CA
(2) Waters Corp., Milford, MA
(3) InPharm Tech., Stephenson, MI

Roundtable Conference Report: The Importance of Hydrodynamics in Dissolution Testing

Roundtable was held at the AAPS National Meeeting, November 1997, Boston, MA

Volume 5, Issue 2, May 1998

Two - Tier Dissolution Testing

Vivian A. Gray
DuPont Merck Pharmaceuticals, Wilmington, DE

Bathless Dissolution: Validation of System Performance

Gerald Brinker and Beth Goldstein
Distek, Inc., Brunswick, NJ

Comparative Evaluation of Mixing Dynamics in USP Apparatus 2 Using Standard USP Vessels and Peak Vessels

Charles C. Collins and Renuka R. Nair
Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA·Meeting News

Volume 5, Issue 3, August 1998

Application of In Vitro Release Methods to Assure Product Performance of Semisolid Dosage Forms Before and After Certain Post-Approval Changes

Vinod P. Shah, Jerome Elkins, Donald Schuirmann, Francis Pelsor, Surendra Shrivastava, Wilson DeCamp, Paul Schwartz and Roger Williams
Office of Pharmaceutical Science, Center for Drug Evaluation and Research, Food and Drug Administration, , Rockville, MD

Dissolved Oxygen as a Measure for De - and Reaeration of Aqueous Media for Dissolution Testing

Steffen M. Diebold and Jennifer B. Dressman
Institut für Pharmazeutische Technologie, J. W. Goethe-Universitat Frankfurt, Germany

"Biopharmacy is Back" -Meeting Report: The Role of the Biopharmaceutics Classification System and In Vitro - In Vivo Correlations in the Approval of Oral Drug Products

Inaugural Dissolution Discussion Group Meeting


Volume 5, Issue 4,

Dissolution Tests for ER Products

Barbara Sievert and Dr. Martin Siewert
Hoechst Marion Roussel AG
Frankfurt, Germany


Biopharmaceutics Classification System:Interview with Prof. Gordon Amidon

Collaborative Development of Two-Tier Dissolution Testing for Gelatin Capsules and Gelatin-Coated Tablets Using Enzyme-Containing Media

Vibration- What Is It and How Does It Affect Dissolution Testing?

Charles C. Collins, Ph.D.
Duquesne University
Pittsburgh, PA