2008 Issues

February 2008 Volume 15 Issue 1


IVIVC: Methods and Applications in Modified-Release Product Development

Harald Rettig and Jana Mysicka
BioVista LLC, Riehen, Switzerland

Technical Evaluation of a Fiber-Optic Probe Dissolution System

Li Liu1, Gifford Fitzgerald2, Matthew Embry1, Ricardo Cantu1, and Brian Pack1
1Eli Lilly and Company, Indianapolis, IN
2University of Notre Dame, Chemistry Department, South Bend, IN

Monitoring Dissolution Rate of Amiodarone Tablets by a Multiple Fiber-Optic Sensor System

Turghun Muhammad1, Jide Wang1, Mei Li-wan2, and Jian Chen2
1College of Chemistry & Chemical Engineering, Xinjiang University, Urumqi 830046, China
2College of Pharmacy, Xinjiang Medical University, Urumqi 830054, China

Technical Note: Why Is Vibration an Issue for Dissolution Testing?

John Burmicz
Pharma Test GmbH Hainburg. Germany

Book Review: Dissolution Theory, Methodology, and Testing Edited by Anthony Palmieri III

Peter Scott
Avatar Pharmaceutical Services Marlborough, MA

Question & Answer Section

Margareth Marques and William Brown
United States Pharmacopeia, Rockville,MD

May 2008 Volume 15 Issue 2


Comparison of Dialysis and Dispersion Methods for In Vitro Release Determination of Drugs from Multilamellar Liposomes

Gamal Shazly, Thomas Nawroth, and Peter Langguth
Institute of Pharmacy, Johannes Gutenberg-University Mainz, Germany

USP Responses to Comments on Stimuli Article, "Proposed Change to Acceptance Criteria for Dissolution Performance Verification Testing"

Walter W. Hauck, Todd L. Cecil, William Brown, Darrell R. Abernethy, William F. Koch, Roger L. Williams
United States Pharmacopeia, Rockville, MD

Effect of Superdisintegrants on Dissolution of Cationic Drugs

J. Balasubramaniam1, K. Bindu1, V. U. Rao1, D. Ray2, R. Haldar2, and A. W. Brzeczko3
1International Specialty Products (India) Pvt. Ltd., Somajiguda, Hyderabad ñ 500 082, India
2International Specialty Products, Wayne, NJ
3ISP Pharma Systems LLC, Columbia, MD

Proposed Design of a Dissolution Apparatus for Vaginal Formulations Containing Probiotics

Vinita Kale, Rashmi Trivedi, and Pratik Muley
Sharad Pawar College of Pharmacy, Wanadongri, Nagpur India

Development of Discriminating Method for Dissolution of Aceclofenac Marketed Formulations

Tejal Soni1, Chirag Nagda2, Tejal Gandhi2, and N.P. Chotai3
1Department of Pharmaceutics, Anand Pharmacy College, Anand, Gujarat, India
2Department of Pharmaceutics, Indukaka College of Pharmacy, New Vallabh-Vidyanagar, Gujarat, India
3Department of Pharmaceutics, A. R. College of Pharmacy, Vallabh-Vidyanagar, Gujarat, India

Question & Answer Section

Margareth Marques and William Brown
United States Pharmacopeia, Rockville,MD

August 2008 Volume 15 Issue 3


New Dissolution Method for Mesalamine Tablets and Capsules

Monica C. Chuong1, J. Mark Christensen2, and James W. Ayres2
1Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences-Boston, Boston, MA
2Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR

Physicochemical Characterization and Dissolution Study of Solid Dispersions of Furosemide with Polyethylene Glycol 6000 and Polyvinylpyrrolidone K30

Rakesh P. Patel, Dhaval J. Patel, Dipen B. Bhimani, and Jayvadan K. Patel
Department of Pharmaceutics, S.K. Patel College of Pharmaceutical Education and Research, Ganpat University, Gujarat, India

Dissolution Stability Study of Cefadroxil Extemporaneous Suspensions

Noelia L. Gonzalez Vidal1,2, Patricia D. Zubata1, Laura D. Simionato1, and Maria T. Pizzorno1,2
1C�tedra Control de Calidad de Medicamentos, Facultad de Farmacia y Bioqu�mica, Universidad de Buenos Aires, Buenos Aires, Argentina
2C�tedra Control de Calidad de Medicamentos, Departamento de Biolog�a, Bioqu�mica y Farmacia, Universidad Nacional del Sur, Bah�a Blanca, Argentina

Meeting Report: AAPS Workshop on the Role of Dissolution in QbD and Drug Product Life Cycle

Kailas Thakker1 and Vivian Gray2
1Analytical Solutions, Inc., Durham, NC
2Dissolution Technologies, Hockessin, DE

Question & Answer Section

Margareth Marques and William Brown
United States Pharmacopeia, Rockville,MD

November 2008 Volume 15 Issue 4


A GoñNoGo Gauge for USP Apparatus 1 Baskets

Kevin Coleman Bynum1, Abe S. Kassis2, and Tarun Patel2
1Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Rd., Ridgefield, CT
2Novartis Pharmaceuticals, One Health Plaza, East Hanover, NJ

Evaluation of Drug Adsorption to Membrane Filters under Biowaiver Test Conditions

Kevin Kiehm and Jennifer B. Dressman
Institute of Pharmaceutical Technology, J. W. Goethe University, Max von Laue-Str. 9, 60438 Frankfurt am Main, Germany

Impact of Sample Preparation on Dissolution Testing: Drug Binding and Extractable Impurities and Their Effect on Dissolution Data

Vivek Joshi1, Jason Blodgett1, Jesmi George1, and Jeff Brinker1
1Millipore Corp., Bioscience Division, 17 Cherry Hill Drive, Danvers, MA
2Distek Inc., 12 North Center Dr, North Brunswick, NJ

Comparison of In Vitro Dissolution Profiles of Oxcarbazepine-HP β-CD Tablet Formulations with Marketed Oxcarbazepine Tablets

Nirav Patel1, Narendra Chotai2, Jayvadan Patel3, Tejal Soni1, Julan Desai1, and Rajnikant Patel4
1Anand Pharmacy College, Opp. Town Hall, Nr, Grid. Anand, Gujarat, India
2A. R. College of Pharmacy & G. H. Patel Institute of Pharmacy, Vallabh Vidyanagar, Gujarat, India
3Nootan Pharmacy College, Visnagar, Gujarat, India
4Kalol Institute of Pharmacy, Kalol, Gujarat, India

Question & Answer Section

Margareth Marques and William Brown
United States Pharmacopeia, Rockville,MD