2008 Issues

February 2008 Volume 15 Issue 1

IVIVC: Methods and Applications in Modified-Release Product Development Harald Rettig and Jana Mysicka BioVista LLC, Riehen, Switzerland Technical Evaluation of a Fiber-Optic Probe Dissolution System Li Liu1, Gifford Fitzgerald2, Matthew Embry1, Ricardo Cantu1, and Brian Pack1 1Eli Lilly and Company, Indianapolis, IN 2University of Notre Dame, Chemistry Department, South Bend, IN Monitoring Dissolution Rate of Amiodarone Tablets by a Multiple Fiber-Optic Sensor System Turghun Muhammad1, Jide Wang1, Mei Li-wan2, and Jian Chen2 1College of Chemistry & Chemical Engineering, Xinjiang University, Urumqi 830046, China 2College of Pharmacy, Xinjiang Medical University, Urumqi 830054, China Technical Note: Why Is Vibration an Issue for Dissolution Testing? John Burmicz Pharma Test GmbH Hainburg. Germany Book Review: Dissolution Theory, Methodology, and Testing Edited by Anthony Palmieri III Peter Scott Avatar Pharmaceutical Services Marlborough, MA Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD

May 2008 Volume 15 Issue 2

Comparison of Dialysis and Dispersion Methods for In Vitro Release Determination of Drugs from Multilamellar Liposomes Gamal Shazly, Thomas Nawroth, and Peter Langguth Institute of Pharmacy, Johannes Gutenberg-University Mainz, Germany USP Responses to Comments on Stimuli Article, "Proposed Change to Acceptance Criteria for Dissolution Performance Verification Testing" Walter W. Hauck, Todd L. Cecil, William Brown, Darrell R. Abernethy, William F. Koch, Roger L. Williams United States Pharmacopeia, Rockville, MD Effect of Superdisintegrants on Dissolution of Cationic Drugs J. Balasubramaniam1, K. Bindu1, V. U. Rao1, D. Ray2, R. Haldar2, and A. W. Brzeczko3 1International Specialty Products (India) Pvt. Ltd., Somajiguda, Hyderabad ñ 500 082, India 2International Specialty Products, Wayne, NJ 3ISP Pharma Systems LLC, Columbia, MD Proposed Design of a Dissolution Apparatus for Vaginal Formulations Containing Probiotics Vinita Kale, Rashmi Trivedi, and Pratik Muley Sharad Pawar College of Pharmacy, Wanadongri, Nagpur India Development of Discriminating Method for Dissolution of Aceclofenac Marketed Formulations Tejal Soni1, Chirag Nagda2, Tejal Gandhi2, and N.P. Chotai3 1Department of Pharmaceutics, Anand Pharmacy College, Anand, Gujarat, India 2Department of Pharmaceutics, Indukaka College of Pharmacy, New Vallabh-Vidyanagar, Gujarat, India 3Department of Pharmaceutics, A. R. College of Pharmacy, Vallabh-Vidyanagar, Gujarat, India Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD

August 2008 Volume 15 Issue 3

New Dissolution Method for Mesalamine Tablets and Capsules Monica C. Chuong1, J. Mark Christensen2, and James W. Ayres2 1Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences-Boston, Boston, MA 2Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR Physicochemical Characterization and Dissolution Study of Solid Dispersions of Furosemide with Polyethylene Glycol 6000 and Polyvinylpyrrolidone K30 Rakesh P. Patel, Dhaval J. Patel, Dipen B. Bhimani, and Jayvadan K. Patel Department of Pharmaceutics, S.K. Patel College of Pharmaceutical Education and Research, Ganpat University, Gujarat, India Dissolution Stability Study of Cefadroxil Extemporaneous Suspensions Noelia L. Gonzalez Vidal1,2, Patricia D. Zubata1, Laura D. Simionato1, and Maria T. Pizzorno1,2 1C�tedra Control de Calidad de Medicamentos, Facultad de Farmacia y Bioqu�mica, Universidad de Buenos Aires, Buenos Aires, Argentina 2C�tedra Control de Calidad de Medicamentos, Departamento de Biolog�a, Bioqu�mica y Farmacia, Universidad Nacional del Sur, Bah�a Blanca, Argentina Meeting Report: AAPS Workshop on the Role of Dissolution in QbD and Drug Product Life Cycle Kailas Thakker1 and Vivian Gray2 1Analytical Solutions, Inc., Durham, NC 2Dissolution Technologies, Hockessin, DE Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD

November 2008 Volume 15 Issue 4

A GoñNoGo Gauge for USP Apparatus 1 Baskets Kevin Coleman Bynum1, Abe S. Kassis2, and Tarun Patel2 1Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Rd., Ridgefield, CT 2Novartis Pharmaceuticals, One Health Plaza, East Hanover, NJ Evaluation of Drug Adsorption to Membrane Filters under Biowaiver Test Conditions Kevin Kiehm and Jennifer B. Dressman Institute of Pharmaceutical Technology, J. W. Goethe University, Max von Laue-Str. 9, 60438 Frankfurt am Main, Germany Impact of Sample Preparation on Dissolution Testing: Drug Binding and Extractable Impurities and Their Effect on Dissolution Data Vivek Joshi1, Jason Blodgett1, Jesmi George1, and Jeff Brinker1 1Millipore Corp., Bioscience Division, 17 Cherry Hill Drive, Danvers, MA 2Distek Inc., 12 North Center Dr, North Brunswick, NJ Comparison of In Vitro Dissolution Profiles of Oxcarbazepine-HP β-CD Tablet Formulations with Marketed Oxcarbazepine Tablets Nirav Patel1, Narendra Chotai2, Jayvadan Patel3, Tejal Soni1, Julan Desai1, and Rajnikant Patel4 1Anand Pharmacy College, Opp. Town Hall, Nr, Grid. Anand, Gujarat, India 2A. R. College of Pharmacy & G. H. Patel Institute of Pharmacy, Vallabh Vidyanagar, Gujarat, India 3Nootan Pharmacy College, Visnagar, Gujarat, India 4Kalol Institute of Pharmacy, Kalol, Gujarat, India Question & Answer Section Margareth Marques and William Brown United States Pharmacopeia, Rockville,MD